|Mugabe appeals for private sector help in AIDS war (2004-06-16)|
|HARARE (Reuters) – Zimbabwe President Robert Mugabe urged the private sector on Wednesday to help his cash-strapped government provide essential drugs to combat an AIDS pandemic he described as one of the greatest challenges facing the country.|
Official figures show that 24.6 percent of Zimbabwe’s adult population is infected with the HIV virus that causes AIDS, one of the highest rates in the world.
|Minor HIV protease mutations point to antiretroviral failure |
Source : J Infect Dis 2004;189:1983-1987
|NEW YORK (Reuters Health) – Minor mutations of 36I and 101/V in HIV protease can predict the appearance of a mutation associated with resistance to protease inhibitors (PIs), European researchers report in the June 1st issue of the Journal of Infectious Diseases.|
Dr. Carlo Federico Perno of the University of Rome Tor Vergata and colleagues, who note that 36I is seen in about 25% of HIV clade B and more than 80% of non-clade B viruses, came to this conclusion after studying 93 previously drug-naive patients who experienced failure of their first PI -based antiretroviral regimens.
|Fuzeon should be used when CD4 counts are above 100m cells per liter: panel |
Source : AIDS 2004;18:1137-1146. 2004-06-22
|NEW YORK (Reuters Health) – The fusion inhibitor enfuvirtide (Fuzeon) should optimally be started when CD4 cell counts are above 100 million cells per liter and virema is below 100,000 copies/mL, according to a panel of HIV-treating physicians with knowledge and experience in using the anti-HIV agent.|
|Southern Africa seen in "death spiral" on AIDS, food shortages |
|JOHANNESBURG (Reuters) – Southern Africa is in a death spiral as AIDS exacerbates food shortages and government and social networks teeter close to collapse, the head of the U.N. World Food Programme (WFP) said on Tuesday.|
"If a 747 aircraft crashed every hour, there’d be an international outcry. That’s the death toll we’re facing but there is inadequate collective outrage," WFP Executive Director James Morris said at the end of a tour in the region, the worst hit worldwide by the global AIDS epidemic.
|OraSure gets HIV-2 test approval in US |
|CHICAGO (Reuters) – U.S. regulators approved OraSure Technologies Inc.’s saliva test for detecting HIV-2, the company said on Wednesday.|
OraSure had received approval in March for a saliva test of HIV-1 that gives quick results. With the latest U.S. Food and Drug Administration approval, OraSure said it plans to market a combined test for use in physicians’ offices and public health clinics as a rapid means of detecting HIV-1 and HIV-2.
|Low CD4 count should not preclude HAART |
Source : J Acquir Immune Defic Syndr 2004;36:702-713
|NEW YORK (Reuters Health) – A long-term analysis of the evolution of CD4+ T cell counts in HIV patients on highly active antiretroviral therapy (HAART) suggests immune recovery is possible even in patients with low baseline CD4 levels.|
In the June 1st issue of the Journal of the Acquired Immunodeficiency Syndrome, Dr.